Our Peer-Reviewed Scientific Publications

Stem Cell Educator Therapy in Type 1 Diabetes

	Reversal of Type 1 Diabetes via Islet beta Cell Regeneration Following Immune Modulation by Cord Blood-Derived Multipotent Stem Cells [Read Article] Journal: BMC Medicine. 10(1): 3, January 2012 Yong Zhao*, Zhaoshun Jiang, Tingbao Zhao, et al.
	Modulation of autoimmune T-Cell memory by Stem Cell Educator therapy: phase 1/2 clinical trial [Read Article] Journal: EBioMedicine. 2: 2024-2036, December 2015 Authors: Elias Delgado, Marcos Perez-Basterrechea, et al., Yong Zhao*.
	Platelets-derived mitochondria display embryonic stem cell markers and improve pancreatic islet β-cell function in humans [Read Article] Journal: STEM CELLS Translational Medicine. 6: 1684-1697, July 2017 Yong Zhao*, Zhaoshun Jiang, Elias Delgado, et al.

Stem Cell Educator Therapy in Type 2 Diabetes

	Targeting insulin resistance via the immune modulation of cord blood-derived multipotent stem cells by the Stem Cell Educator Therapy [Read Article] Journal: Diabetes. 61: S1, A-75, 2012 Authors: Yong Zhao*, Zhaoshun Jiang, Mingliang Ye, et al.
	Targeting insulin resistance in type 2 diabetes via immune modulation of cord blood-derived multipotent stem cells (CB-SCs) in stem cell educator therapy: phase I/II clinical trial [Read Article] Journal: BMC Medicine. 11(1):160, July 2013 Authors: Yong Zhao*, Zhaoshun Jiang, Mingliang Ye, et al.

Stem Cell Educator Therapy in Alopecia Areata

	Hair Regrowth in Alopecia Areata Patients Following Stem Cell Educator Therapy [Read Article] Journal: BMC Medicine. 13: 87, April 2015 Authors: Yanjia Li, Baoyong Yan, et al., Yong Zhao

Invited Review Articles

	Stem Cell Educator therapy in type 1 diabetes: from the bench to clinical trials. [Read Article] Journal: Autoimmunity Reviews. 21: 103058, 2022 Authors: Yong Zhao, Colette M. Knight, Zhaoshun Jiang, Elias Delgado, Anne Marie Van Hoven, Steven Ghanny, Zhiguang Zhou, Huimin Zhou, Haibo Yu, Wei Hu, Heng Li, Xia Li, Marcos Perez-Basterrechea, Laura Zhao, Yeqian Zhao, Joseph Giangola, Rona Weinberg, Theodore Mazzone
	Clinical Translational Potentials of Stem Cell-Derived Extracellular Vesicles in Type 1 Diabetes. [Read Article] Journal: Frontiers in Endocrinology. Jan. 12, 2022 Authors: Wei Hu, … and Yong Zhao*.
	Therapeutic Potentials of Extracellular Vesicles for the Treatment of Diabetes and Diabetic Complications. [Read Article] Journal: Int J Mol Sci 21(14):5163, 2020 Authors: Wei Hu, … and Yong Zhao*
	New hope for type 1 diabetes mellitus: Stem Cell Educator therapy. [Read Article] Journal: Chinese Journal of Diabetes. 22 (3): 194 – 199, February 2014 Authors: Yong Zhao*
	Stem Cell Educator Therapy and the treatment of Type 1 Diabetes. [Read Article] Journal: Chinese Journal of Diabetes Mellitus. 6 (2): 69 -72, February 2014 Authors: Yong Zhao* and Zhiguang Zhou.
	Stem Cell Educator Therapy and Induction of Immune Balance, [Read Article] Journal: Current Diabetes Reports. 12: online 2012 Authors: Yong Zhao*
	New hope for type 2 diabetics: targeting insulin resistance through the immune modulation of stem cells. [Read Article] Journal: Autoimmunity Reviews. 11: 137-142, 2011 Authors: Yong Zhao*, Zhao shun Jiang, Chengshan Guo
	Human cord blood stem cells and the journey to a cure for type 1 diabetes. [Read Article] Journal: Autoimmunity Reviews. 10:103-107, 2010 Authors: Yong Zhao*, Theodore Mazzone

A Novel Function Of Mitochondria In Cellular Reprogramming

	Immune Modulation of Platelet-Derived Mitochondria on Memory CD4+ T Cells in Humans. [Read Article] Journal: International Journal of Molecular Sciences. 21(17): 6295. August 31, 2020. Haibo Yu, Wei Hu, Xiang Song, Yong Zhao*
	Generation of Multipotent Stem Cells from Adult Human Peripheral Blood Following the Treatment with Platelet-Derived Mitochondria. [Read Article] Journal: Cells. 9, 1350, May 2020 Haibo Yu, Wei Hu, Xiang Song and Yong Zhao *
	Generation of Hematopoietic-Like Stem Cells from Adult Human Peripheral Blood Following Treatment with Platelet-Derived Mitochondria. [Read Article] Journal: International Journal of Molecular Sciences. 21, 4249. June 15, 2020. Haibo Yu, Wei Hu, Xiang Song, Yong Zhao*

Molecular Mechanism Underlying The Immune Modulation Of CB-SCs

	Differentiation of Monocytes into Phenotypically Distinct Macrophages After Treatment with Human Cord Blood Stem Cell (CB-SC)-Derived Exosomes. [Read Article] Journal: Journal of Visualized Experiments (JoVE). 10.3791/61562, November 2020 Authors: Wei Hu, Xiang Song, Haibo Yu, Jingyu Sun, Yong Zhao*
	Released Exosomes Contribute to the Immune Modulation of Cord Blood-Derived Stem Cells (CB-SC). [Read Article] Journal: Frontiers in Immunology. 11: 165, 2020 Authors: Wei Hu, Xiang Song, Haibo Yu, Jingyu Sun, Yong Zhao*

Identification Of Peripheral Blood-Derived Insulin-Producing Cells (PB-IPC)

	A unique human blood-derived cell population displays high potential for producing insulin. [Read Article] Journal: Biochemical and Biophysical Research Communications. 360: 205-211, 2007 Authors: Yong Zhao*, Z Huang, P Lazzarini, et al.

Differentiation Of CB-SCs Into Dopamine Neurons

	Human cord blood-derived multipotent stem cells (CB-SCs) treated with all-trans-retinoic acid (ATRA) give rise to dopamine neurons. [Read Article] Journal: Biochemical and Biophysical Research Communications. 419(1):110-6, 2012 Authors: Xiaohong Li, Heng Li, et al., Yong Zhao*

First Demonstration That CB-SCs Display Immune Modulation

	Immune regulation of T lymphocyte by a newly characterized human umbilical cord blood stem cell. [Read Article] Journal: Immunology Letters. 108:78-87, 2007 Authors: Yong Zhao*, Zhihua Huang, Meirigeng Qi, et al.

Identification Of Human Cord Blood-Derived Multipotent Stem Cells (CB-SCs)

	Identification of pluripotent stem cells from umbilical cord blood with embryonic and hematopoietic characteristics. [Read Article] Journal: Experimental Cell Research. 312: 2454-2464, 2006 Authors: Yong Zhao*, Honglan Wang, Theodore Mazzone.